Biology Is Love

 BCL2 PROTEINS REGULATES INTRINSIC PATHWAY OF APOPTOSIS                                                                                   -EISHIKA DAS In Intrinsic apoptotic pathway, mitochondrion plays a central role by releasing cytochrome C. The defining event during intrinsic apoptotic pathway Is mitochondrial outer membrane permeabilization or MOMP . Following MOMP, cytochrome c, are released into the cytosol. Once in the cytoplasm, cytochrome c binds to adaptor protein APAF1 . This interaction leads to hydrolysis of the bound dATP to dADP and a change in the conformation of APAF-1.  APAF-1 assembles into a heptameric complex, the apoptosome . The APAF-1 proteins in the apoptosome then recruit initiator procaspase-9. The incorporation of procaspase-9 into the apoptosome ...

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  Why Oxytocin and Vasopressin called as 'neuro hormone'?      -souti das                            The posterior pitutary secretes two hormone oxytocin and vasopressin(ADH).The hormones are synthesized within the cell bodies of large magnocellular neurons lying in the supraoptic and paraventricular nuclei (PVN) of the hypothalamus.                            The posterior pituitary hormones are transported in association with specific proteins, called neurophysins , along the axons of the neurons to end in those nerve terminals which lie within the posterior lobe. Prior to secretion, these hormones are stored in secretory granules either in the nerve terminals or in the varicosites called herring bodies . The hormones are secreted in response to nerve impulses originating in the supraoptic and PVN and enter the capill...

TOP 5 TEXT BOOK ON BIOLOGY FOR CLASS 11 AND 12                                                                                                                        - Malay Nayak There are various board student in India. Like CBSE and ISC mainly are the central board, and there is many state board from various state of INDIA. Today we will tell you about top 5 Biology book you should read for your board exam as well as preparation for NEET-UG 1. NCERT Biology Textbook For Class - 11 And Class - 12 It is called the bible of  NEET 95% question of NEET comes form this book Every  student should read this book to clear your concepts  📚🔖 BUY NOW     🔖📚  CLIC...

  Time Dependent Potentiation of Insulin secretion   Glucose causes time dependent potentiation(TDP) of insulin secretion; that is exposure of islets beta cells to high glucose enhances insulin release in response to the stimulus applied later.

Wolf-Chaikoff Effect It is a reduction in thyroid hormone levels caused by ingestion of a large amount of iodine(more than 2mg/day) which suppresses NADPH oxidase activity as well as NIS & TPO genes expression. Jan Wolff and Isreal Lyon Chaikoff first reported that injection of iodine in rats almost completely inhibited " Organification of iodine " in the thyroid gland by an " Autoregulatory phenomenon ".  The Wolff-Chaikoff effect lasts several days(~10 days), after which it is disappeared by a process known as " Escape Phenomenon " which is described by resumption of normal organification of iodine and normal TPO function.                     The Wolff-Chaikoff effect can be used as a treatment principle against hyperthyroidism by infusion of a large amount of iodine to suppress the thyroi d gland.  By- Souti Das image source- twitter

RESOURCESS USE IN BIOINFORMATICS 👉Sequence database: 1. Uniprot: UniProt is the Universal Protein resource, a central repository of protein data created by combining the Swiss-Prot, TrEMBL and PIR-PSD databases. Web adress:   https://www.uniprot.org/

 COVID-19 - Eishika Das,  -Soumyaprabha Ganguly HISTORY:  Coronavirus disease 2019  ( COVID-19 ) is an  infectious disease  caused by  severe acute respiratory syndrome coronavirus 2  (SARS-CoV-2) The disease was first identified in 2019 in  Wuhan , the capital of  Hubei , China, and has since spread globally, resulting in the  2019–20 coronavirus pandemic . According to the World Health Organization (WHO), viral diseases continue to emerge and represent a serious issue to public health. In the last twenty years, several viral epidemics such as the severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002 to 2003 beginning in China and involving two dozen countries with approximately 8000 cases and 800 deaths , and H1N1 influenza in 2009, have been recorded. Most recently, the Middle East respiratory syndrome coronavirus (MERS-CoV) was first identified in Saudi Arabia in 2012 approximately 2,500 cases and 800...