Skip to main content

Top 6 Online Database used in Bioinformatics

RESOURCESS USE IN BIOINFORMATICS

👉Sequence database:

1. Uniprot: UniProt is the Universal Protein resource, a central repository of protein data created by combining the Swiss-Prot, TrEMBL and PIR-PSD databases.

Web adress:  https://www.uniprot.org/

               

2. NCBI: The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health (NIH).

                   

                    Website -   http://www.ncbi.nlm.nih.gov/

  The NCBI houses a series of databases relevant to biotechnology and biomedicine and is an important resource for bioinformatics tools and services. Major databases include GenBank for DNA sequences and PubMed, a bibliographic database for the biomedical literature. Other databases include the NCBI Epigenomics database. All these databases are available online through the Entrez search engine. NCBI was directed by David Lipman, one of the original authors of the BLAST sequence alignment program and a widely respected figure in bioinformatics.

3. Ensembl: Ensembl genome database project is a joint scientific project between the European Bioinformatics Institute and the Wellcome Trust Sanger Institute, which was launched in 1999 in response to the imminent completion of the Human Genome Project. Ensembl aims to provide a centralized resource for geneticists, molecular biologists and other researchers studying the genomes of our own species and other vertebrates and model organisms.Ensembl is one of several well known genome browsers for the retrieval of genomic information.

Website: www.ensembl.org


                    

👉 Structure database:

1. PDB: The Protein Data Bank (PDB) is a database for the three-dimensional structural data of large biological molecules, such as proteins and nucleic acids. The data, typically obtained by X-ray crystallography, NMR spectroscopy, or, increasingly, cryo-electron microscopy, and submitted by biologists and biochemists from around the world, are freely accessible on the Internet via the websites of its member organisations.

Website: www.rcsb.org

                    

2. NDB: The NDB contains information about experimentally-determined nucleic acids and complex assemblies.Use the NDB to perform searches based on annotations relating to sequence, structure and function, and to download, analyze, and learn about nucleic acids.

Website: ndbserver.rutgers.edu

                     


3. Pfam: Pfam is a database of protein families that includes their annotations and multiple sequence alignments generated using hidden Markov models. The most recent version, Pfam 32.0, was released in September 2018 and contains 17,929 families. The general purpose of the Pfam database is to provide a complete and accurate classification of protein families and domains.

Website: pfam.xfam.org

       

BOOK OF BIOINFORMATICS FROM AMAZON

THANK YOU


Labels:

Comments

Post a Comment

please share it with your friends and students

Popular posts from this blog

TOP 5 BOOKS ON HUMAN PHYSIOLOGY

Post a Comment
Read more

Process of lactation/lactogenesis

 Process of lactation/lactogenesis - Souti Das To provide milk to neonates, at the end of pregnancy around the time when the young is born, the mammary glands undergo a process that initiates milk secretion, called lactogenesis. The human mammary gland is composed of about 20 lobes, each with an excretory lactiferous duct that opens at the nipple. Loves, in turn, are composed of several lobules, which contains secretory structures called alveoli, and the terminal portions of the ducts. The epithelia of the alveoli and ducts are composed of apical luminal ductal or alveolar cells and a myoepithelial cell layer on the basal side of the epithelium. Myoepithelial cells are stellate, smooth muscle-like cells, and contraction of these cells in response to oxytocin expel milk from the lumina of the alveoli and ducts. Source: White and Porterfield  4th Edition     Lactogenesis has two main phases. The initiation phase (Lactogenesis I) is characterized by increased express...
3 comments
Read more

COVID 19 - A brief details about COVID-19 , HISTORY, STRUCTURE, MODE OF TRANSMISSION, MODE OF ACTION and SYMPTOMS

 COVID-19 - Eishika Das,  -Soumyaprabha Ganguly HISTORY:  Coronavirus disease 2019  ( COVID-19 ) is an  infectious disease  caused by  severe acute respiratory syndrome coronavirus 2  (SARS-CoV-2) The disease was first identified in 2019 in  Wuhan , the capital of  Hubei , China, and has since spread globally, resulting in the  2019–20 coronavirus pandemic . According to the World Health Organization (WHO), viral diseases continue to emerge and represent a serious issue to public health. In the last twenty years, several viral epidemics such as the severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002 to 2003 beginning in China and involving two dozen countries with approximately 8000 cases and 800 deaths , and H1N1 influenza in 2009, have been recorded. Most recently, the Middle East respiratory syndrome coronavirus (MERS-CoV) was first identified in Saudi Arabia in 2012 approximately 2,500 cases and 800...
Post a Comment
Read more