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DBT-JRF brief notes [Bioinformatics] PART -1

 Facts and information about Bioinformatics especially for DBT-JRF:  [Part -1] These notes are only for the students who are not interested in Bioinformatics but want to solve and memorize the common questions in DBT-JRF.   DOT BLOT: Pairwise sequence similarity   Protein database: Try to recall the names and the subcategories.   E- value:  BLAST: Have a look at the difference between local and global alignment.  If a nucleotide sequence encoding a protein is known and a homologous protein to be identified, --> the best analysis tool is BLASTx. Read the following:  Substitution Matrix: [Along with PAM and BLOSUM] These notes are based on the PYQs.  Similarity search: