DBT-JRF brief notes [Bioinformatics] PART -1

Facts and information about Bioinformatics especially for DBT-JRF: [Part -1]

These notes are only for the students who are not interested in Bioinformatics but want to solve and memorize the common questions in DBT-JRF.

DOT BLOT: Pairwise sequence similarity

Protein database:

Try to recall the names and the subcategories.

E- value:

BLAST:

Have a look at the difference between local and global alignment.

If a nucleotide sequence encoding a protein is known and a homologous protein to be identified, --> the best analysis tool is BLASTx.

Read the following:

Substitution Matrix: [Along with PAM and BLOSUM]

These notes are based on the PYQs.

Similarity search:

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