DBT-JRF notes [Crabtree and Warburg effect]

Crabtree effect:

The name is given by an English Biochemist Herbert Grace Crabtree.

This effect is referred to as the production of ethanol in aerobic conditions rather than biomass by yeast cells at high external glucose concentrations through the TCA cycle.

This is basically the decrease in the rate of electron transport due to the mass action of the elevated phosphorylation ratio.

Warburg effect:

This effect is referred to as an increase in the rate of glucose uptake and the production of lactate in aerobic conditions. The discoverer of this effect,

Warburg hypothesized that this effect is mainly due to the dysfunctional mitochondria, observed in the tumor cells, predominantly found in the cancer developmental cells.

The Crabtree-Warburg effect interprets that the avoidance of a decrease in ATP is observed in those conditions where higher glucose uptake is found than the downstream processing capability of the second phase of the glycolysis.

Comments

Why oxytocin and vasopressin called as 'neuro hormone'?

Why Oxytocin and Vasopressin called as 'neuro hormone'? -souti das The posterior pitutary secretes two hormone oxytocin and vasopressin(ADH).The hormones are synthesized within the cell bodies of large magnocellular neurons lying in the supraoptic and paraventricular nuclei (PVN) of the hypothalamus. The posterior pituitary hormones are transported in association with specific proteins, called neurophysins , along the axons of the neurons to end in those nerve terminals which lie within the posterior lobe. Prior to secretion, these hormones are stored in secretory granules either in the nerve terminals or in the varicosites called herring bodies . The hormones are secreted in response to nerve impulses originating in the supraoptic and PVN and enter the capill...

TOP 5 BOOKS ON HUMAN PHYSIOLOGY

Are Apple Seeds Poisonous? The Truth Behind Cyanide Content

Cyanide in Apple!! 🍏 Apple 🍎seeds are often regarded as a healthy snack that is packed with numerous nutritional benefits. However, there is a concern that apple seeds contain cyanide, a toxic substance that can cause harm to the human body. In this article, we will discuss the truth behind apple seeds containing cyanide, how much cyanide is present, and whether eating apple seeds is safe or not. The truth behind apple seeds containing cyanide Apple seeds contain a small amount of cyanide, which is a poisonous chemical compound that can be harmful to the body if ingested in large amounts. The cyanide is present in the form of amygdalin, which is a glycoside that is found in the seeds of various fruits, including apples. When apple seeds are crushed or chewed, amygdalin is released and can be converted into hydrogen cyanide, a poisonous gas. How much cyanide is present in apple seeds? The amount of cyanide present in apple seeds varies depending on the variety of apple and the ...

Biology Is Love

Search This Blog